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SHR Neuro Cancer Cardio Lipid Metab Microb

Hauer, A.
Cow's milk allergy. Immune mechanisms and clinical manifestations
MONATSSCHR KINDERHEILK 2006 154: 406-+. Doi: 10.1007/s00112-006-1335-2
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Leading authors Med Uni Graz: Hauer Almuthe
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Abstract:: Allergies in childhood are increasing steadily, and cow's milk allergy often represents the beginning of the so-called allergic march. To date, the two best understood pathomechanisms allow a distinction between IgE-mediated and non-IgE-mediated allergic reactions: IgE-mediated reactions lead mostly to clinical reactions of quick onset that can be proven by laboratory tests (skin prick, positive specific antibodies), Non-IgE-mediated reactions have a more delayed clinical manifestation, and conclusive laboratory tests are lacking. Also, eosinophilic gastrointestinal disorders may be triggered by cow's milk proteins. The main organ systems involved are the gastrointestinal tract, the skin, and the respiratory tract. Anaphylactic reactions are possible, but rarer. Treatment consists of dietary exclusion of cow's milk proteins for at least the 1st year of life or until tolerance has been proven clinically, which is usually the case by the end of the 3rd year.
Find related publications in this database (Keywords): allergy; cow's milk proteins; infants; eosinophils; gastrointestinal tract