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Gewählte Publikation:

Bonelli, RM; Mayr, BM; Niederwieser, G; Reisecker, F; Kapfhammer, HP.
Ziprasidone in Huntington's disease: the first case reports.
J Psychopharmacol. 2003; 17(4):459-460 Doi: 10.1177%2F0269881103174009 (- Case Report)
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Führende Autor*innen der Med Uni Graz
Bonelli Raphael
Co-Autor*innen der Med Uni Graz
Kapfhammer Hans-Peter
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Abstract:
Huntington's disease (HD) is a relentlessly progressive neuropsychiatric disorder with an underlying autosomal dominantly inherited genetic defect. Classical antipsychotics (i.e. phenothiazines or butyrophenones) are the most used medication to reduce the (probably dopamine-born) choreiform hyperkinesias. Ziprasidone is the latest of a new class of atypical antipsychotics; it has not been studied so far in this indication. We report three genetically confirmed HD patients who improved significantly in several categories of the motor scale of the Unified HD Rating Scale.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Dopamine Antagonists - therapeutic use
Female - therapeutic use
Humans - therapeutic use
Huntington Disease - drug therapy
Male - drug therapy
Middle Aged - drug therapy
Piperazines - therapeutic use
Thiazoles - therapeutic use

Find related publications in this database (Keywords)
antipsychotic medications
chorea
Huntington's disease
UHDRS
Ziprasidone
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