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Patacchini, R; Lecci, A; Holzer, P; Maggi, CA.
Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature.
TRENDS PHARMACOL SCI. 2004; 25: 1-3.
Doi: 10.1016%2Fj.tips.2003.11.005
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- Co-authors Med Uni Graz
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Holzer Peter
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- Abstract:
- The tachykinin family has recently been extended by the discovery of a third tachykinin gene encoding previously unknown mammalian tachykinins (hemokinin 1, endokinin A and endokinin B) that have a widespread peripheral distribution and a tachykinin NK(1) receptor selectivity. This and the identification of other tachykinin-like peptides such as C14TKL-1 and virokinin raise many questions about the roles played by tachykinins in peripheral tissues and render terms such as 'neurokinins' and 'SP receptor' inappropriate.
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Animals -
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Humans -
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Species Specificity -
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Tachykinins - genetics
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Terminology - genetics