Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Strunk, D; Grube, R; Stadelmeyer, E; Linkesch, W.
Dendritic cell deficiency in early B cell chronic lymphocytic leukemia.
HAEMATOLOGICA. 2004; 89(1): 111-112.
[OPEN ACCESS]
Web of Science
PubMed
- Leading authors Med Uni Graz
- Strunk Dirk
- Co-authors Med Uni Graz
- Linkesch Werner
- Stadelmeyer Elke
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- Abstract:
- We compared the frequency, phenotype and function of blood dendritic cells (DC) and their precursors in patients with untreated B cell chronic lymphocytic leukemia (CLL) and in normal individuals. The numbers of CD11c(+) and CD123(+) blood DC were significantly reduced in CLL patients already at diagnosis and these cells showed diminished antigen uptake and perturbed maturation. The number of monocytes was normal and the number of CD34(+) progenitor cells increased in the CLL patients' blood.
- Find related publications in this database (using NLM MeSH Indexing)
- Dendritic Cells - metabolism
- Humans - metabolism
- Leukemia, B-Cell, Chronic - blood
- Phenotype - blood
- Find related publications in this database (Keywords)
- CLL
- dendritic cells
- leukemia
- lymphoma
- cancer