Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Soyer, HP; Argenziano, G; Zalaudek, I; Corona, R; Sera, F; Talamini, R; Barbato, F; Baroni, A; Cicale, L; Di Stefani, A; Farro, P; Rossiello, L; Ruocco, E; Chimenti, S.
Three-point checklist of dermoscopy. A new screening method for early detection of melanoma.
DERMATOLOGY 2004 208: 27-31.
Doi: 10.1159/000075042
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Soyer Hans Peter
- Co-Autor*innen der Med Uni Graz
- Zalaudek Iris
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- Abstract:
- BACKGROUND: Dermoscopy used by experts has been demonstrated to improve the diagnostic accuracy for melanoma. However, little is known about the diagnostic validity of dermoscopy when used by nonexperts. OBJECTIVE: To evaluate the diagnostic performance of nonexperts using a new 3-point checklist based on a simplified dermoscopic pattern analysis. METHODS: Clinical and dermoscopic images of 231 clinically equivocal and histopathologically proven pigmented skin lesions were examined by 6 nonexperts and 1 expert in dermoscopy. For each lesion the nonexperts assessed 3 dermoscopic criteria (asymmetry, atypical network and blue-white structures) constituting the 3-point method. In addition, all examiners made an overall diagnosis by using standard pattern analysis of dermoscopy. RESULTS: Asymmetry, atypical network and blue-white structures were shown to be reproducible dermoscopic criteria, with a kappa value ranging from 0.52 to 0.55. When making the overall diagnosis, the expert had 89.6% sensitivity for malignant lesions (tested on 68 melanomas and 9 pigmented basal cell carcinomas), compared to 69.7% sensitivity achieved by the nonexperts. Remarkably, the sensitivity of the nonexperts using the 3-point checklist reached 96.3%. The specificity of the expert using overall diagnosis was 94.2% compared to 82.8 and 32.8% achieved by the nonexperts using overall diagnosis and 3-point checklist, respectively. CONCLUSION: The 3-point checklist is a valid and reproducible dermoscopic algorithm with high sensitivity for the diagnosis of melanoma in the hands of non-experts. Thus it may be applied as a screening procedure for the early detection of melanoma.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Diagnosis, Differential -
- Female -
- Humans -
- Male -
- Melanoma - diagnosis
- Observer Variation - diagnosis
- Reproducibility of Results - diagnosis
- Retrospective Studies - diagnosis
- Sensitivity and Specificity - diagnosis
- Skin Neoplasms - diagnosis
- Find related publications in this database (Keywords)
- dermoscopy
- melanoma
- pigmented skin lesions