Medizinische Universität Graz - Research portal
Selected Publication:
Krippl, P; Langsenlehner, U; Renner, W; Yazdani-Biuki, B; Wolf, G; Wascher, TC; Paulweber, B; Weitzer, W; Leithner, A; Samonigg, H.
The 870G>A polymorphism of the cyclin D1 gene is not associated with breast cancer.
Breast Cancer Res Treat. 2003; 82(3):165-168
Doi: 10.1023/B:BREA.0000004372.20461.33
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Krippl Peter
- Co-authors Med Uni Graz
- Langsenlehner Uwe
- Leithner Andreas
- Renner Wilfried
- Samonigg Hellmut
- Wascher Thomas
- Weitzer Werner
- Yazdani-Biuki Babak
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- Abstract:
- A common 870G > A polymorphism in the gene for cyclin D1, CCND1, has been linked to alternative splicing and cancer susceptibility. To analyze its role for breast cancer, we determined the CCND1 genotype in 500 breast cancer patients and 500 controls. CCND1 genotype frequencies were similar among patients and controls. The CCND1 genotype was furthermore not associated with tumor characteristics. We conclude that the CCND1 870G > A polymorphism is not associated with breast cancer.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Breast Neoplasms - genetics
- Case-Control Studies - genetics
- DNA Primers - genetics
- Female - genetics
- Genes, bcl-1 - genetics
- Genetic Predisposition to Disease - genetics
- Humans - genetics
- Middle Aged - genetics
- Polymerase Chain Reaction - genetics
- Polymorphism, Genetic - genetics
- Find related publications in this database (Keywords)
- breast cancer
- cyclin D1
- epidemiology
- gene polymorphism
- genetics