Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kreuzer, C; Urlesberger, B; Maurer, U; Müller, W.
Transient periventricular echodensities (TPE) in preterm infants under 1500 gramms: an analysis of the outcome of the last 10 years
Klin Padiatr. 2003; 215(5):252-256
Doi: 10.1055/s-2003-42667
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Kreuzer Christina
- Urlesberger Berndt
- Co-Autor*innen der Med Uni Graz
- Müller Wilhelm
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- Abstract:
- BACKGROUND: The aim of our study was to analyze neurodevelopmental outcome in preterm infants with TPE. PATIENTS: 46 preterm infants with a birthweight (BW) < or = 1500 g were included in the study. They all had TPE in parieto-occipital location (some combined with frontal flares). Exclusion criteria were PVL II-IV, intraventricular hemorrhage, asphyxia and isolated frontal TPE. METHOD: We analyzed ultrasound scans (1992 - 2001) of patients with TPE (diameter > 1 cm, visible in both sagittal and coronal planes, duration > 7 days), and neurological follow-up visits (date of demission, corrected age of 4, 8, 12 months, and after that every 2 years until 6 years of age) regarding the neurodevelopmental outcome. We devided the patients in group 1 (duration of TPE 8 - 14 days) and group 2 (duration of TPE > 14 days) and then analyzed the groups regarding neurodevelopmental disorders and factors increasing the risk of occurrence of TPE. RESULTS: From 1992 - 2001 578 children < or = 1500 g were admitted at our department. 48 patients (8,3 %) fulfilled the entry criteria, 2 of them died, so 46 were included in the study. In group 1 (10 patients) the median gestational age (GA) was 28 weeks (range 25 - 31), median BW 1075 g (range 685 - 1430), 6 children were neurologically unimpaired, one developed a motor handicap, and 3 a psychomotor retardation. In group 2 (36 patients) the median GA was 28 weeks (range 25 - 35), median BW 1034,5 g (range 540 - 1470), 24 patients were neurologically unimpaired, 7 developed a motor handicap, and 5 a psychomotor retardation. No statistical difference was found between the groups neither in neurodevelopmental outcome nor factors increasing the risk of the occurrence of TPE. CONCLUSIONS: Obviously, the finding of TPE is of clinical relevance already at a duration of only 7 days regarding later neurological development.
- Find related publications in this database (using NLM MeSH Indexing)
- Age Factors -
- Cerebral Ventricles - ultrasonography
- Child - ultrasonography
- Child, Preschool - ultrasonography
- Data Interpretation, Statistical - ultrasonography
- Follow-Up Studies - ultrasonography
- Gestational Age - ultrasonography
- Humans - ultrasonography
- Infant - ultrasonography
- Infant, Newborn - ultrasonography
- Infant, Premature - ultrasonography
- Infant, Very Low Birth Weight - ultrasonography
- Leukomalacia, Periventricular - ultrasonography
- Neurologic Examination - ultrasonography
- Psychomotor Disorders - diagnosis
- Time Factors - diagnosis
- Find related publications in this database (Keywords)
- preterm infants
- neurodevelopmental outcome
- transient periventricular echodensities