Gewählte Publikation:
Scheltens, P; Barkhof, F; Fazekas, F.
White-matter changes on MRI as surrogate marker
INT PSYCHOGERIATR. 2003; 15: 261-265.
Doi: 10.1017/S104161020300930X
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- Co-Autor*innen der Med Uni Graz
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Fazekas Franz
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- Abstract:
- This article reviews the use of white-matter changes as identified on MRI as a surrogate marker in clinical trials on vascular dementia. As of yet, insufficient evidence is present to implement rating or volumetric assessment of the burden of white-matter changes as surrogate marker in such trials, in view of the limited sensitivity to change of current methods and the high measurement error.
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dementia
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white matter
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MRI
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clinical trials
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vascular
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