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Gewählte Publikation:

Schmidt, R; Schmidt, H; Kapeller, P; Fazekas, F.
Slow progression of white-matter changes
INT PSYCHOGERIATR. 2003; 15: 173-176. Doi: 10.1017/S1041610203009153
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Führende Autor*innen der Med Uni Graz
Schmidt Reinhold
Co-Autor*innen der Med Uni Graz
Fazekas Franz
Kapeller Peter
Schmidt Helena
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Abstract:
A three-year follow-up of 273 participants (mean age 60 years) of the Austrian Stroke Prevention Study provides the first information on the rate, clinical predictors, and cognitive consequences of MRI white-matter lesions in elderly individuals without neuropsychiatric disease. Lesion progression was found in 17.9% of individuals over a time period of 3 years. Diastolic blood pressure and early confluent or confluent white-matter hyperintensities at baseline were the only significant predictors of white-matter hyperintensity progression. Lesion progression had no influence on the course of neuropsychologic test performance over the observational period, but the statistical power of this analysis was low.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Brain - blood supply
Brain Ischemia - pathology
Cerebrovascular Circulation - physiology
Disease Progression - physiology
Humans - physiology
Magnetic Resonance Imaging - physiology
Risk Factors - physiology

Find related publications in this database (Keywords)
white-matter lesions
risk factors
cerebral small-vessel disease
cognition
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