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Selected Publication:
Hentsch, A; Aschauer, MA; Balzer, JO; Brossmann, J; Busch, HP; Davis, K; Douek, P; Ebner, F; van Engelshoven, JM; Gregor, M; Kersting, C; Knüsel, PR; Leen, E; Leiner, T; Loewe, C; McPherson, S; Reimer, P; Schäfer, FK; Taupitz, M; Thurnher, SA; Tombach, B; Wegener, R; Weishaupt, D; Meaney, JF.
Gadobutrol-enhanced moving-table magnetic resonance angiography in patients with peripheral vascular disease: a prospective, multi-centre blinded comparison with digital subtraction angiography.
Eur Radiol. 2003; 13(9):2103-2114
Doi: 10.1007/s00330-003-1844-5
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Aschauer Manuela
- Ebner Franz
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- Abstract:
- The purpose of this study was to compare moving-table three-dimensional contrast-enhanced magnetic resonance angiography (CE MRA), using 1.0-mol gadobutrol, with intra-arterial digital subtraction angiography (i.a. DSA) for evaluation of pelvic and peripheral arteries in patients with peripheral arterial occlusive disease. A total of 203 patients were examined in a prospective, multi-centre study at 1.0/1.5 T. Ten vessel segments of one leg were evaluated on-site and by three independent blinded reviewers off-site. One hundred eighty-two patients were evaluable in blinded reading. For pelvis and thigh, there was statistically significant diagnostic agreement between CE MRA and i.a. DSA on-site (94%) and off-site (86-88%). Overall, for detection of clinically significant stenoses, 93% sensitivity and 90% specificity were achieved in on-site evaluation, with 71-76 and 87-93% off-site; for detection of occlusion, sensitivity and specificity on-site were 91 and 97%, with 75-82 and 94-98% off-site. Evaluation was more sensitive on-site than off-site for detection of stenoses and occlusion, whereas specificity was similar. The CE MRA with 1.0-mol gadobutrol gave results comparable to those of i.a. DSA for the larger arteries of pelvis and thigh. Results for calf arteries were compromised by spatial resolution and technical limitations.
- Find related publications in this database (using NLM MeSH Indexing)
- Angiography, Digital Subtraction -
- Arterial Occlusive Diseases - diagnosis
- Contrast Media - diagnosis
- Double-Blind Method - diagnosis
- Female - diagnosis
- Humans - diagnosis
- Image Enhancement - methods
- Leg - blood supply
- Magnetic Resonance Angiography - methods
- Male - methods
- Middle Aged - methods
- Organometallic Compounds - diagnostic use
- Pelvis - blood supply
- Peripheral Vascular Diseases - diagnosis
- Prospective Studies - diagnosis
- Sensitivity and Specificity - diagnosis
- Find related publications in this database (Keywords)
- arteriography
- contrast-enhanced MR angiography arteriosclerosis
- peripheral arterial occlusive disease
- blinded reading