Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pizzichetta, MA; Massone, C; Grandi, G; Pelizzo, G; Soyer, HP.
Morphologic changes of acquired melanocytic nevi with eccentric foci of hyperpigmentation (Bolognia sign) assessed by dermoscopy.
Arch Dermatol. 2006; 142(4):479-483
Doi: 10.1001/archderm.142.4.479
(- Case Report)
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Massone Cesare
- Soyer Hans Peter
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- BACKGROUND: Melanocytic nevi with eccentric foci of hyperpigmentation ("Bolognia sign") can be considered as a melanoma-simulating type of acquired melanocytic nevus. We report on the morphologic changes of this type of melanocytic nevus over a 39-month period of dermoscopic follow-up. OBSERVATIONS: A 5-year-old girl had a 4-mm brown papule with a peripheral blue-black area on her right upper arm. The eccentric focus of the hyperpigmentation corresponded dermoscopically to a blue-gray area of pigmentation associated with irregular brown-black globules or dots and partially with a superficial black network. After 39 months, a globular type of acquired melanocytic nevus was detectable, which clinically and dermoscopically appeared to be completely benign. A nearly identical situation was observed in 5 other melanocytic nevi, underlining the involution of the pigmented foci in these nevi. The histopathologic diagnoses of 2 lesions were consistent with a compound type of acquired melanocytic nevus with eccentric foci of hyperpigmentation. CONCLUSIONS: Dermoscopy allows identification of a morphologic pathway of modifications, probably typical for this type of melanocytic nevus in children, and therefore enables avoidance of surgical excision with attendant hypertrophic scarring in children. Conversely, in adults, when dermoscopic follow-up of melanocytic nevi reveals eccentric foci of hyperpigmentation, surgical excision of the lesion is indicated.
- Find related publications in this database (using NLM MeSH Indexing)
- Child, Preschool -
- Dermoscopy - methods
- Diagnosis, Differential -
- Female -
- Humans -
- Hyperpigmentation - diagnosis Hyperpigmentation - pathology
- Melanoma - diagnosis Melanoma - pathology
- Nevus, Pigmented - diagnosis Nevus, Pigmented - pathology
- Skin Neoplasms - diagnosis Skin Neoplasms - pathology