Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Ramschak-Schwarzer, S; Lipp, R; Passath, A; Warnkross, H; Stiegler-Heinz, C; Dobnig, H; Wascher, T; Leb, G.
Clinical value of the various methods of ACTH determination
Acta Med Austriaca. 1993; 20(3):81-84
Web of Science
PubMed
- Co-Autor*innen der Med Uni Graz
- Dobnig Harald
- Lipp Rainer
- Wascher Thomas
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- Abstract:
- We determined 293 plasma-ACTH levels out of 49 patients. In 12 patients with various pituitary diseases 168 samples were collected during a standardized pituitary stimulation test. For this purpose we used the following kits: the DYNOtest ACTH and LUMItest ACTH and Allegro HS-ACTH test. Additionally, morning ACTH levels were analyzed from 49 patients using Allegro HS ACTH test and DYNOtest ACTH. Regarding ACTH concentrations during pituitary stimulation the clinical usefulness of the 3 named tests were comparable. Pair differences of morning ACTH levels were not statistically significant. In a setting of a wide range of ACTH levels all 3 trials proved appropriate for making a diagnosis. Practicability of all 3 tests was similar. For all 3 methods incubation can be done overnight which saves time. Reagents can be reused when frozen immediately after reconstitution.
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- ACTH
- Hypophysis
- Pituitary Stimulation Test