Medizinische Universität Graz - Research portal
Selected Publication:
Bonelli, RM; Niederwieser, G; Lahousen, T; Hofmann, P.
Zotepine in Huntington's disease.
Hum Psychopharmacol. 2003; 18(3):227-229
Doi: 10.1002/hup.474
(- Case Report)
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Bonelli Raphael
- Co-authors Med Uni Graz
- Hofmann Peter
- Lahousen-Luxenberger Theresa
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- Abstract:
- The authors report a patient with Huntington's disease (HD) presenting with severe chorea. The motor scale of the unified HD rating scale (UHDRS-I) revealed 81 points. Motor function clearly improved with zotepine, until she reached an UHDRS-I of 34 points on day 7 of treatment. The patient was stable for at least 12 weeks. The improvement includes all seven categories of the UHDRS-I, especially chorea, gait and oral function. This is the first description of zotepine in HD. Our findings suggest that zotepine is useful in the treatment of HD chorea. Controlled trials of its use in HD would be welcome.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
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- Chorea - drug therapy
- Dibenzothiepins - therapeutic use
- Female - therapeutic use
- Humans - therapeutic use
- Huntington Disease - drug therapy
- Treatment Outcome - drug therapy
- Find related publications in this database (Keywords)
- Huntington's disease
- zotepine
- severe chorea