Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kaemmerer, H; Bauer, U; Stein, JI; Lemp, S; Bartmus, D; Hoffmann, A; Niesert, S; Osmers, R; Fratz, S; Rossa, S; Lange, PE; Beitzke, A; Schneider, KT; Hess, J.
Pregnancy in congenital cardiac disease: an increasing challenge for cardiologists and obstetricians -- a prospective multicenter study.
Z Kardiol. 2003; 92(1):16-23
Doi: 10.1007/s00392-003-0880-0
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Beitzke Albrecht
- Stein Joerg-Ingolf
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- Abstract:
- OBJECTIVES: Aim of this study was to assess the occurrence of pregnancy-related complications of mother and child during pregnancy, delivery and puerperium in women with CCD prospectively. STUDY DESIGN, POPULATION: This prospective multicenter study included 122 pregnancies in 106 women with CCD (72 with, 34 without previous cardiac surgery). Patient age was 17-44, median 26 years. Cardiac and non-cardiac complications, mode of delivery, abortion, and CCD of the newborn were assessed. RESULTS: Initially all women were in Functional Class I or II. Worsening during pregnancy occurred in 25.5% (n=27), mainly during the second and third trimester. Significant problems due to bleeding, hypertension, rhythm disturbances, endocarditis, liver congestion, increasing cyanosis or death, occurred in 11.3%. Twelve per cent of deliveries were premature. Five women had therapeutic abortion, nine spontaneous abortions, nine preterm births, and one intrauterine death. Seventy-nine per cent (n=85) delivered spontaneously; 21.3% (n=23) had caesarean section. Of the 111 live born children, 5.4% (n=6) had a CCD. CONCLUSIONS: Most women with CCD and a good functional class before pregnancy tolerate pregnancy without major problems. However, pregnancy may induce serious cardiac and obstetric complications. The specific risks require an individualized multidisciplinary patient-management by experienced physicians.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Cause of Death -
- Cesarean Section -
- Combined Modality Therapy -
- Extraction, Obstetrical -
- Female -
- Fetal Death - epidemiology
- Germany - epidemiology
- Heart Defects, Congenital - mortality
- Humans - mortality
- Infant, Newborn - mortality
- Neonatal Screening - mortality
- Obstetric Labor Complications - mortality
- Patient Care Team - mortality
- Pregnancy - mortality
- Pregnancy Complications, Cardiovascular - mortality
- Pregnancy Outcome - mortality
- Prospective Studies - mortality
- Puerperal Disorders - mortality
- Survival Analysis - mortality
- Find related publications in this database (Keywords)
- pregnancy
- congenital cardiac disease
- congenital heart disease
- cardiac and obstetric complications
- delivery