Medizinische Universität Graz - Research portal
Selected Publication:
Legat, FJ; Maier, A; Dittrich, P; Zenahlik, P; Kern, T; Nuhsbaumer, S; Frossard, M; Salmhofer, W; Kerl, H; Müller, M.
Penetration of fosfomycin into inflammatory lesions in patients with cellulitis or diabetic foot syndrome.
Antimicrob Agents Chemother. 2003; 47(1):371-374
Doi: 10.1128/AAC.47.1.371-374.2003
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- Leading authors Med Uni Graz
- Legat Franz
- Co-authors Med Uni Graz
- Kerl Helmut
- Maier Alfred
- Salmhofer Wolfgang
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- Abstract:
- We investigated the distribution of the broad-spectrum antibiotic fosfomycin in infected soft tissue of patients with uncomplicated cellulitis of the lower extremities or diabetic foot infection using in vivo microdialysis. Our findings suggest that fosfomycin exhibits good and similar penetration into the fluid in the interstitial space in inflamed and noninflamed soft tissue in patients.
- Find related publications in this database (using NLM MeSH Indexing)
- Area Under Curve -
- Cellulitis - metabolism
- Diabetic Foot - metabolism
- Female -
- Fosfomycin - blood
- Fosfomycin - pharmacokinetics
- Half-Life -
- Humans -
- Male -
- Microdialysis -
- Middle Aged -
- Tissue Distribution -