Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Legat, FJ; Maier, A; Dittrich, P; Zenahlik, P; Kern, T; Nuhsbaumer, S; Frossard, M; Salmhofer, W; Kerl, H; Müller, M.
Penetration of fosfomycin into inflammatory lesions in patients with cellulitis or diabetic foot syndrome.
Antimicrob Agents Chemother. 2003; 47(1):371-374
Doi: 10.1128/AAC.47.1.371-374.2003
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- Führende Autor*innen der Med Uni Graz
- Legat Franz
- Co-Autor*innen der Med Uni Graz
- Kerl Helmut
- Maier Alfred
- Salmhofer Wolfgang
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- Abstract:
- We investigated the distribution of the broad-spectrum antibiotic fosfomycin in infected soft tissue of patients with uncomplicated cellulitis of the lower extremities or diabetic foot infection using in vivo microdialysis. Our findings suggest that fosfomycin exhibits good and similar penetration into the fluid in the interstitial space in inflamed and noninflamed soft tissue in patients.
- Find related publications in this database (using NLM MeSH Indexing)
- Area Under Curve -
- Cellulitis - metabolism
- Diabetic Foot - metabolism
- Female -
- Fosfomycin - blood
- Fosfomycin - pharmacokinetics
- Half-Life -
- Humans -
- Male -
- Microdialysis -
- Middle Aged -
- Tissue Distribution -