Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Aigner, RM; Fueger, GF; Schimpl, G; Sauer, H; Nicoletti, R.
Cholescintigraphy in the evaluation of bile flow after Roux-en-Y hepatico-jejunostomy and hepatico-antrostomy in infants with choledochal cysts.
Pediatr Radiol. 1997; 27(11):850-854
Doi: 10.1007/s002470050253
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Aigner Reingard
- Co-Autor*innen der Med Uni Graz
- Nicoletti Rudolf
- Schimpl Guenther
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- Abstract:
- Background The study tests the hypothesis that stasis of bile in the Roux-en-Y hepatico-jejunostomy (RYJS) loop might facilitate biliary reflux and cause cholangitis, whereas quicker transit times in hepatico-antrostomy (HAST) might prevent cholangitis. Materials and methods. Cholescintigraphy was performed using Tc99m-trimethyl-Br-IDA in seven RYJS patients and in five HAST patients. Results. The time to peak (T-max) within the RYJS loop occurred between 18 and 50 min postinjection in all patients and the mean transit time (MTT) ranged between 42 and 69 min in 5/7 patients. Prolonged clearance of the tracer from the liver was seen in 2/7 RYJS patients, in whom the MTT was 77 and 240 min, respectively. In the HAST group the T-max within the anastomosed antrum occurred between 5 and 33 min postinjection, and the MTT ranged between 42 and 44 min in 2/5 patients, Protracted tracer uptake in the liver in one patient and localised tracer retention in the left hepatic bile ducts in 2/5 patients caused prolonged MTTs, Recurrent cholangitis and diarrhoea occurred in 4/7 RYJS patients, but in none of the HAST patients. Elevated gastrin levels after RYJS contrasted sharply to normal gastrin levels after HAST. Conclusion. The findings on cholescintigraphy did not differ significantly between RYJS and HAST and provided no explanation for the distinctly different postoperative clinical course of both surgical methods, Nevertheless: we consider cholescintigraphy to be art efficient and cost-effective diagnostic modality for evaluation of the surgical outcome as regards biliary flow.
- Find related publications in this database (using NLM MeSH Indexing)
- Anastomosis, Roux-en-Y -
- Bile - radionuclide imaging Bile - secretion
- Biliary Tract - radionuclide imaging
- Child -
- Child, Preschool -
- Choledochal Cyst - physiopathology Choledochal Cyst - radionuclide imaging Choledochal Cyst - surgery
- Female -
- Follow-Up Studies -
- Humans -
- Imino Acids - diagnostic use
- Jejunostomy -
- Liver - surgery
- Male -
- Organotechnetium Compounds - diagnostic use
- Postoperative Period -
- Pyloric Antrum - surgery
- Radiopharmaceuticals - diagnostic use
- Time Factors -