Medizinische Universität Graz - Research portal
Selected Publication:
Reichenpfader, B; Zehner, R; Klintschar, M.
Characterization of a highly variable short tandem repeat polymorphism at the D2S1242 locus
ELECTROPHORESIS 1999 20: 514-517.
Doi: 10.1002/(SICI)1522-2683(19990301)20:3<514::AID-ELPS514>3.0.CO;2-V
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Reichenpfader Barbara
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- We report the evaluation of short tandem repeat (STR) locus D2S1242 (GDB ID G00-309-429) for forensic purposes, investigated by polymerase chain reaction (PCR) amplification and both native and denaturating polyacrylamide gel electrophoresis in 147 unrelated Austrians. No deviations from Hardy-Weinberg expectations were observed. The mean exclusion chance (MEC) was 0.669, the discriminating power (DP) was 0.947, and the observed heterozygosity rate was 0.856. An allelic ladder consisting of eight sequenced alleles (141-167 and 175 bp) was constructed. Sequence analysis revealed that the locus comprised two repeat motifs varying in number between alleles GAAA and GAAG. According to the number of tetranucleotide repeats the smallest allele was designated as 10 and the largest allele as 18.
- Find related publications in this database (using NLM MeSH Indexing)
- Alleles -
- Base Sequence -
- Genetic Markers -
- Humans -
- Molecular Sequence Data -
- Polymorphism, Genetic -
- Research Support, Non-U.S. Gov't -
- Tandem Repeat Sequences -
- Find related publications in this database (Keywords)
- Microsatellite
- Sequencing
- Forensic
- Short Tandem Repeat