Gewählte Publikation:
Haeusler, MC; Berghold, A; Stoll, C; Barisic, I; Clementi, M; EUROSCAN Study Group.
Prenatal ultrasonographic detection of gastrointestinal obstruction: results from 18 European congenital anomaly registries.
Prenat Diagn. 2002; 22(7):616-623
Doi: 10.1002/pd.341
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Haeusler Martin
- Co-Autor*innen der Med Uni Graz
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Berghold Andrea
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- Abstract:
- Objectives We evaluated the prenatal detection of gastrointestinal obstruction (GIO. including atresia, stenosis, absence or fistula) by routine ultrasonographic examination in an unselected Population all over Europe.Methods Data from 18 congenital malformation registries in 11 European Countries were analysed. These multisource registries used the same methodology. All fetuses/neonates with GIO confirmed within I week after birth who had prenatal sonography and were born during the Study period (1 July 1996 to 31 December 1998) were included.Results There were 670 793 births in the area covered and 349 fetuses/neonates had GIO. The prenatal detection rate of GIO was 34%; of these 40% were detected <24 weeks of gestation (WG). A total of 31% (60/192) of the isolated GIO were detected prenatally, as were 38%, (59/157) of the associated GIO (p = 0.26). The detection rate was 25% for esophageal obstruction (31/122). 52% for duodenal obstruction (33/64), 40% for small intestine obstruction (27/68) and 29% for large intestine obstruction (28/95) (p = 0.002). The detection rate was higher in countries with a policy of routine obstetric ultrasound. Fifteen percent of pregnancies were terminated (51/349). Eleven of these had chromosomal anomalies. 31 multiple malformations, eight non-chromosomal recognized syndromes, and one isolated GIO. The participating registries reflect the various national policies for termination of pregnancy (TOP), but TOPs after 24 WG (11151) do not appear to be performed more frequently in countries with a liberal TOP policy.Conclusion This European study shows that the detection rate of GIO depends oil the screening policy and oil the sonographic detectability of GIO Subgroups. Copyright (C) 2002 John Wiley Soils. Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
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Adult -
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Congenital Abnormalities -
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Diagnostic Tests, Routine -
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Digestive System Abnormalities - epidemiology Digestive System Abnormalities - ultrasonography
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Digestive System Abnormalities - epidemiology
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Female -
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Humans -
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Infant, Newborn -
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Intestinal Obstruction - epidemiology Intestinal Obstruction - ultrasonography
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Male -
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Mass Screening -
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Pregnancy -
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Registries -
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Sex Factors -
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Ultrasonography, Prenatal -
- Find related publications in this database (Keywords)
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birth defects
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intestinal atresia
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gastrointestinal obstruction
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fetal ultrasound screening
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registry