Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Jürgens, G; Költringer, P.
Cerebrovascular disease and Lp(a): its role in atherosclerotic plaque formation and vessel wall elasticity of the carotid arteries.
Chem Phys Lipids. 1994; 67-68(3):429-434
Doi: 10.1016/0009-3084(94)90166-X
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PubMed
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- Führende Autor*innen der Med Uni Graz
- Jürgens Günther
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- Abstract:
- Lp(a) was found to represent an independent risk factor of extracranial carotid atherosclerosis (CA). Here we report on an investigation with 808 subjects randomly selected from stroke patients as well as from asymptomatic subjects. Serum levels of Lp(a), total cholesterol (TC), HDL-C and the ratios of TC/HDL-C and LDL-C/HDL-C correlated highly significantly with the carotid score using a univariate test. Performing a discriminant analysis, the following ranking was obtained: Lp(a), HDL-C, LDL-C/HDL-C. Evaluation of the vessel wall elasticity in 746 subjects revealed Lp(a) to be the only highly significant parameter. Thus, Lp(a) has to be taken into consideration when establishing a risk profile of CA.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Arteriosclerosis - blood
- Carotid Arteries - physiopathology
- Carotid Artery Diseases - blood
- Cerebrovascular Disorders - blood
- Elasticity - blood
- Female - blood
- Humans - blood
- Lipoprotein(a) - blood
- Male - blood
- Middle Aged - blood
- Risk Factors - blood
- Find related publications in this database (Keywords)
- Lp(A)
- Lipoproteins
- Serum Lipids
- Cerebrovascular Disease
- Carotid Atherosclerosis