Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Direkt zur Navigaton springen.
Direkt zum Inhalt springen.

Navigation/Suche

Gewählte Publikation:

Weger, M; Haas, A; Stanger, O; El-Shabrawi, Y; Temmel, W; Maier, R; Berghold, A; Haller-Schober, EM.
Chlamydia pneumoniae seropositivity and the risk of nonarteritic ischemic optic neuropathy.
OPHTHALMOLOGY 2002 109: 749-752. Doi: 10.1016%2FS0161-6420%2801%2901031-4
Web of Science PubMed FullText FullText_MUG

Führende Autor*innen der Med Uni Graz: Weger Martin
Co-Autor*innen der Med Uni Graz: Berghold Andrea; El-Shabrawi Yosuf; Haas Anton; Haller-Schober Eva-Maria; Maier Richard; Temmel Werner
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: OBJECTIVE: To determine whether IgG antibodies to Chlamydia pneumoniae are associated with nonarteritic ischemic optic neuropathy (NAION). DESIGN: Retrospective case-control study. PARTICIPANTS: The study cohort consisted of 71 consecutive patients with NAION and 71 controls matched for age and gender. MAIN OUTCOME MEASURES: Serum immunoglobulin G (IgG) antibody titers to Chlamydia pneumoniae. RESULTS: Patients with NAION had significantly higher IgG antibody titers to C. pneumoniae compared with control subjects (IgG titer > or =1:128: 29 patients versus 15 controls, P = 0.017). The odds ratio for patients with an IgG titer > or =1:128 was 2.56 (95% confidence interval [CI], 1.2-5.5). Adjustment for arterial hypertension, diabetes mellitus, and myocardial infarction resulted in an odds ratio of 3.48 (95% CI, 1.3-9.6). CONCLUSIONS: Our results suggest that elevated titers of IgG antibodies to C. pneumoniae are associated with NAION.
Find related publications in this database (using NLM MeSH Indexing): Aged -; Aged, 80 and over -; Antibodies, Bacterial - blood; Case-Control Studies - blood; Chlamydophila Infections - blood; Chlamydophila pneumoniae - immunology; Eye Infections, Bacterial - blood; Female - blood; Humans - blood; Immunoglobulin G - blood; Male - blood; Middle Aged - blood; Odds Ratio - blood; Optic Neuropathy, Ischemic - blood; Retrospective Studies - blood; Risk Factors - blood