Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Hiti, K; Walochnik, J; Haller-Schober, EM; Faschinger, C; Aspöck, H.
Viability of Acanthamoeba after exposure to a multipurpose disinfecting contact lens solution and two hydrogen peroxide systems.
BRIT J OPHTHALMOL 2002 86: 144-146.
Doi: 10.1136%2Fbjo.86.2.144
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- Führende Autor*innen der Med Uni Graz
- Hiti Klaus
- Co-Autor*innen der Med Uni Graz
- Faschinger Christoph
- Haller-Schober Eva-Maria
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- Abstract:
- BACKGROUND/AIM: Contact lens cases contaminated with Acanthamoeba are a major risk factor for an infection of the eye. In this study the anti-Acanthamoeba activity of three different contact lens storage solutions was tested. METHODS: A new multipurpose contact lens storage solution (Meni Care Plus) and a two step (Titmus H(2)O(2)) and one step (Oxysept Comfort) hydrogen peroxide system were tested for their effects on trophozoites and cysts of three different Acanthamoeba species: A castellanii, A hatchetti, and A lenticulata. RESULTS: After a soaking time of 8 hours (overnight soaking of contact lenses) the Titmus H(2)O(2) 0.6% solution showed very good amoebicidal effects, while Oxysept Comfort 3% H(2)O(2) could not effectively destroy the cysts of any of the three tested species. Viable cysts of the species A lenticulata and A hatchetti were still present after exposure to Meni Care Plus (0.0005% PHMB) for 8 hours. CONCLUSION: Not all of the three tested contact lens storage solutions have sufficient amoebicidal effects. The two step peroxide system Titmus H(2)O(2) is a very effective disinfectant contact lens solution in order to avoid a possible Acanthamoeba infection of the eye.
- Find related publications in this database (using NLM MeSH Indexing)
- Acanthamoeba - classification
- Animals - classification
- Biguanides - pharmacology
- Comparative Study - pharmacology
- Contact Lens Solutions - pharmacology
- Disinfectants - pharmacology
- Disinfection - methods
- Equipment Contamination - methods
- Humans - methods
- Hydrogen Peroxide - pharmacology