Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Feigl, B; Haas, A.
Multifocal ERG in central areolar choroidal dystrophy
Ophthalmologe. 2001; 98(11):1074-1078
Doi: 10.1007/s003470170028
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Feigl Beatrix
- Co-Autor*innen der Med Uni Graz
- Haas Anton
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- BACKGROUND: In comparison to full-field ERG a multifocal ERG (mf-ERG) provides functional mapping of the central retina and detection of more localised defects. Central areolar choroidal dystrophy is an autosomal dominant inherited disorder with central atrophy of the choriocapillaries, the retinal pigment epithelium (RPE) and the photoreceptors. Full-field ERG often shows only slight to moderate reductions. The purpose of our study was to investigate the electroretinographic activity of the posterior pole with the mf-ERG in comparison to the photopic full-field ERG in these patients. PATIENTS AND METHODS: We performed a mf-ERG and a photopic full-field ERG in 4 patients with central areolar choroidal dystrophy and in 20 age-matched volunteers who constituted the normal control group. RESULTS: In all patients reductions in b-wave amplitudes of the first order kernel of the mf-ERG in both eyes were evident. Full-field ERG showed decreased b-wave amplitudes in only three eyes. Subnormal amplitudes were found in two eyes and normal amplitudes in three eyes. Additionally ophthalmoscopic lesions were found to a lesser extent than by the mf-ERG. DISCUSSION: The mf-ERG is a valuable tool in detecting central areolar choroidal dystrophy and might be useful in early detection and follow-up, when ophthalmoscopy and full-field ERG are still normal. Moreover it could contribute to differential diagnosis of other retinal diseases of the posterior pole.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Choroid Diseases - diagnosis
- Diagnosis, Differential - diagnosis
- Electroretinography - methods
- Female - methods
- Fluorescein Angiography - methods
- Fundus Oculi - methods
- Humans - methods
- Male - methods
- Middle Aged - methods
- Photoreceptors - physiology
- Find related publications in this database (Keywords)
- multifocal ERG
- mf-ERG
- retiscan
- central areolar choroidal dystrophy