Freigassner, PS; El-Shabrawi, Y.
Optic nerve involvement in syphilis in 4 patients
Klin Monatsbl Augenheilkd. 2001; 218(10):691-694
Doi: 10.1055/s-2001-18393
(- Case Report)
Web of SciencePubMedFullTextFullText_MUG
BACKGROUND: Due to increasing numbers of cases syphilis again becomes more important in ophthalmology. Syphilitic ocular manifestations do not show any typical characteristics and therefore are often not diagnosed although a correct and early diagnosis with adequate therapy is very important for the visual outcome. PATIENTS: We report on four patients with luetic ocular fundus manifestations, who were referred to our clinic with unspecific ocular complaints. Funduscopic examination revealed in all patients a papilledema, which was bilateral in three patients and unilateral in one patient. Additional findings were a non-granulomatous uveitis anterior and a chorioretinitis in both eyes of a 61-year-old HIV positive patient with retinal scars from a bilateral acute retinal necrosis syndrome (ARN), a mild non granulomatous iridocyclitis in a 53-year-old patient and a bilateral chorioretinitis and a cystoid macular edema in a 37-year-old patient. A 54-year-old patient showed a vein branch occlusion. Serological analysis demonstrated active syphilis in all cases and an EBV-infection in two patients. After penicillin therapy the ocular findings resolved. CONCLUSION: In all cases of inflammatory fundus manifestations syphilis should be taken into consideration and serological lues tests should be performed routinely.
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