Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Hofmann, PJ; Nutzinger, DO; Kotter, MR; Herzog, G.
The hypothalamic-pituitary-thyroid axis in agoraphobia, panic disorder, major depression and normal controls.
J Affect Disord. 2001; 66(1):75-77
Doi: 10.1016%2FS0165-0327%2800%2900271-8
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Hofmann Peter
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- BACKGROUND: Much interest has been drawn to the investigation of the hypothalamic-pituitary-thyroid (HPT)-axis in patients suffering from depression or panic disorder. However, there is no data concerning agoraphobia. METHODS: Patients with panic disorder, agoraphobia, major depression were compared to normal controls (total n=88) in respect to HPT axis, obtaining basal TSH and administering a TRH test. RESULTS: Normal controls and agoraphobics showed significantly higher Delta(max) TSH than depressives and panic patients. There were no differences between agoraphobics and normal controls. CONCLUSIONS: Agoraphobia, unlike depression or panic disorder, seems to be less biologically determined in respect to the HPT-axis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Agoraphobia - diagnosis
- Depressive Disorder, Major - diagnosis
- Female - diagnosis
- Humans - diagnosis
- Hypothalamo-Hypophyseal System - physiopathology
- Male - physiopathology
- Panic Disorder - diagnosis
- Reference Values - diagnosis
- Sensitivity and Specificity - diagnosis
- Thyroid Gland - physiopathology
- Thyrotropin - blood
- Thyrotropin-Releasing Hormone - diagnostic use