Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Cerroni, L; Kerl, H.
Primary cutaneous follicle center cell lymphoma.
Leuk Lymphoma. 2001; 42(5):891-900
Doi: 10.3109/10428190109097708
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Cerroni Lorenzo
- Co-Autor*innen der Med Uni Graz
- Kerl Helmut
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- The exact classification of primary cutaneous follicle center cell lymphomas (FCCLs) has been the subject of ongoing debate. In the classification of cutaneous lymphomas proposed by the European Organization for Research and Treatment of Cancer (EORTC)-Cutaneous Lymphoma Project Group, cutaneous follicle center cell lymphoma (FCCL) is defined as a proliferation of centrocytes and centroblasts showing a diffuse pattern of growth in the great majority of cases, and presenting only rarely a true follicular pattern. CD10 and Bcl-2 are usually not expressed by neoplastic cells, and the t(14:18) is absent. By contrast, nodal follicular lymphoma is a tumor with a follicular pattern, characterized by the proliferation of CD10+, Bcl-2+ follicular cells, and by the presence of the t(14;18) in most cases. In this review we outline the clinicopathologic, phenotypic, and molecular features of primary cutaneous FCCL, reviewing criteria for diagnosis and differential diagnosis of this peculiar variant of cutaneous B-cell lymphoma.
- Find related publications in this database (using NLM MeSH Indexing)
- Clone Cells - chemistry Clone Cells - immunology Clone Cells - metabolism
- Cytogenetic Analysis -
- Diagnosis, Differential -
- Humans -
- Immunohistochemistry -
- Immunophenotyping -
- Lymphoma, B-Cell - classification
- Lymphoma, Follicular - classification Lymphoma, Follicular - diagnosis Lymphoma, Follicular - pathology
- Lymphoma, Large B-Cell, Diffuse - classification Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - pathology
- Skin Neoplasms - classification Skin Neoplasms - diagnosis Skin Neoplasms - pathology
- Find related publications in this database (Keywords)
- primary cutaneous follicle center cell lymphoma
- NHL
- extranodal lymphoma
- cutaneous B-cell lymphoma