Medizinische Universität Graz - Research portal
Selected Publication:
Weber, F; Bauer, JW; Sepp, N; Högler, W; Salmhofer, W; Hintner, H; Fritsch, P.
Squamous cell carcinoma in junctional and dystrophic epidermolysis bullosa.
Acta Derm Venereol. 2001; 81(3):189-192
Doi: 10.1080%2F000155501750376285
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- Co-authors Med Uni Graz
- Salmhofer Wolfgang
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- Abstract:
- We report here on three patients suffering from recessive dystrophic epidermolysis bullosa and one suffering from generalized atrophic benign epidermolysis bullosa, all of whom developed cutaneous squamous cell carcinoma. Our observations and a review of the literature suggest that squamous cell carcinoma in generalized atrophic benign epidermolysis bullosa is very infrequent and has a better outcome compared to skin cancer in recessive dystrophic epidermolysis bullosa. These differences could be explained by the distinct pathophysiology and clinical course of each of these variants of epidermolysis bullosa. In contrast to UV-induced skin cancer, the tumours in epidermolysis bullosa develop on distal extremities at sites of chronic wound healing. The cases reported here underline the exceptional importance of early histopathological assessment of suspicious skin lesions in patients with epidermolysis bullosa.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Carcinoma, Squamous Cell - complications
- Epidermolysis Bullosa Dystrophica - complications
- Epidermolysis Bullosa, Junctional - complications
- Female - complications
- Humans - complications
- Male - complications
- Middle Aged - complications
- Skin Neoplasms - complications
- Find related publications in this database (Keywords)
- epidermolysis bullosa dystrophicans Hallopeau-Siemens
- generalized atrophic benign epidermolysis bullosa
- skin cancer