Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schmidt, R; Fazekas, F; Offenbacher, H; Mächler, H; Freidl, W; Payer, F; Rigler, B; Harrison, MI; Lechner, H.
Brain magnetic resonance imaging in coronary artery bypass grafts: a pre- and postoperative assessment.
Neurology. 1993; 43(4):775-778
Doi: 10.1212/WNL.43.4.775
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Führende Autor*innen der Med Uni Graz
- Schmidt Reinhold
- Co-Autor*innen der Med Uni Graz
- Fazekas Franz
- Freidl Wolfgang
- Mächler Heinrich
- Payer Franz
- Rigler Bruno
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- We undertook a study to determine (1) the frequency and prognostic significance of preexisting MRI brain abnormalities in patients undergoing coronary artery bypass grafts (CABG) and (2) whether MRI can detect surgery-related brain damage in 31 neurologically asymptomatic CABG patients (mean age, 61.0 +/- 6.6 years). MRIs were performed within 7 days before and 8 to 17 days after surgery. When we compared the preoperative images with those of 31 age- and risk factor-matched neurologically asymptomatic controls free of cardiac disease (mean age, 60.3 +/- 6.1 years), higher rates of thromboembolic infarcts (16% versus 0%), lacunes (58.1% versus 32.3%), and brainstem lesions (22.6% versus 3.8%) were noted. Subjective rating demonstrated significantly larger ventricles in patients than in controls (p = 0.002). CABG candidates also had significantly increased ventricular-to-intracranial cavity ratios (VICR) as determined by semiquantitative volumetric measurements (6.9 +/- 2.5% versus 4.9 +/- 1.6%; p = 0.0004). Eleven patients had postsurgical complications, with eight having symptoms consistent with diffuse encephalopathy. The only MRI finding that separated encephalopathic from complication-free patients was ventricular size (VICR 9.0 +/- 2.5% versus 4.9 +/- 1.6%; p = 0.006). This difference remained statistically significant after adjustment for the effects of age (p = 0.04). Postoperative MRI consistently failed to demonstrate surgery-related brain damage responsible for the encephalopathy.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Brain Diseases - diagnosis Brain Diseases - epidemiology Brain Diseases - etiology
- Brain Ischemia - diagnosis Brain Ischemia - etiology
- Coronary Artery Bypass - adverse effects
- Coronary Disease - complications Coronary Disease - surgery
- Evaluation Studies as Topic -
- Female -
- Humans -
- Incidence -
- Magnetic Resonance Imaging -
- Male -
- Middle Aged -
- Prognosis -
- Prospective Studies -
- Risk Factors -