Medizinische Universität Graz - Research portal
Selected Publication:
Klintschar, M; al-Hammadi, N; Reichenpfader, B.
Significant differences between Yemenite and Egyptian STR profiles and the influence on frequency estimations in Arabs.
INT J LEGAL MED 2001 114: 211-214.
Doi: 10.1007%2Fs004140000157
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- Co-authors Med Uni Graz
- Reichenpfader Barbara
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- Abstract:
- A population genetic study was performed on Yemenites using the set of nine short tandem repeat loci (STRs) D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. Analysis of the data revealed that all loci were in Hardy-Weinberg equilibrium and evidence of linkage equilibrium was found for only 1 out of 36 locus pairs. At seven loci the allelic distributions found in the Yemenite sample were significantly different from those found for an Arab population sample from Egypt. Nevertheless, we assume that the Yemenite database can be used for Arabs of unknown or foreign (non-Yemenite) origin in the absence of population-specific databases without exerting a significant bias on the biostatistical interpretation. In an experimental set-up (ethnic profile frequency ratio test), the impact of calculating multi-locus profile frequencies for foreign Arab individuals (Egyptians) using the Yemenite database instead of a region-specific one was negligible.
- Find related publications in this database (using NLM MeSH Indexing)
- Arabs - genetics
- Blood Stains - genetics
- Comparative Study - genetics
- DNA Fingerprinting - genetics
- Egypt - genetics
- Genetics, Population - genetics
- Humans - genetics
- Microsatellite Repeats - genetics
- Paternity - genetics
- Tandem Repeat Sequences - genetics
- Yemen - genetics
- Find related publications in this database (Keywords)
- forensics
- DNA
- ethnic profile
- frequency ratio test
- short tandem repeat
- Yemen