Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Huppertz, B.
Evidence for a cGMP gated cation channel in photoreceptor cell membranes of Sepia officinalis.
FEBS LETT 1995 364: 189-192.
Doi: 10.1016/0014-5793(95)00390-U
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Führende Autor*innen der Med Uni Graz
- Huppertz Berthold
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- It is assumed that cyclic nucleotides are involved in signal transduction of invertebrate photoreceptors. In this study, membranes of photoreceptor cells from freshly caught cuttlefish were isolated, and the membrane proteins were reconstituted into proteoliposomes. With the dye Neutral red it was possible to measure cyclic nucleotide induced Na+ fluxes into the liposomes. cGMP and cAMP concentrations for half maximal activation of Na+ fluxes are 77 microM and 224 microM, respectively, with Hill coefficients of 2.0 for cGMP and 2.4 for cAMP. These fluxes may demonstrate the presence of at least one cyclic nucleotide gated cation channel in the membranes of the photoreceptor cells of the invertebrate Sepia officinalis.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Cell Membrane - metabolism
- Cyclic GMP - metabolism
- In Vitro - metabolism
- Ion Channel Gating - metabolism
- Ion Channels - metabolism
- Microscopy, Electron - metabolism
- Mollusca - metabolism
- Photoreceptors, Invertebrate - metabolism
- Proteolipids - metabolism
- Signal Transduction - metabolism
- Find related publications in this database (Keywords)
- INVERTEBRATE PHOTORECEPTOR
- CGMP
- CATION CHANNEL
- RECONSTITUTION
- SEPIA OFFICINALIS