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Gewählte Publikation:

Oettl, K; Greilberger, J; Reibnegger, G.
Dihydroneopterin as a scavenger of nitrogen centered radicals
PTERIDINES 2000 11: 90-93. Doi: 10.1515/pteridines.2000.11.3.90
Web of Science FullText FullText_MUG

 

Führende Autor*innen der Med Uni Graz

Öttl Karl

Co-Autor*innen der Med Uni Graz

Greilberger Joachim

Reibnegger Gilbert

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Abstract:

Dihydroneopterin has recently been shown to either promote or decrease formation of free radicals or radical-mediated reactions, depending on the conditions. We report here the scavenging activity of dihydroneopterin on nitrogen centered radicals. Diphenylpicrylhydrazyl (DPPH) and the radical cation of 2,2 ' -azino-di-[3-ethylbenzthiazoline sulphonate] (ABTS) were used. Dihydroneopterin showed scavenging properties against either compound. In the case of DPPH radical scavenging by dihydroneopterin was comparable with trolox. In the ABTS system, dihydroneopterin had an even better capacity of radical scavenging as compared to trolox.

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