Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Einspieler, C; Kerr, AM; Prechtl, HF.
Abnormal general movements in girls with Rett disorder: the first four months of life.
BRAIN DEVELOP. 2005; 27 Suppl 1: S8-S13.
Doi: 10.1016/j.braindev.2005.03.014
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Einspieler Christa
- Co-Autor*innen der Med Uni Graz
- Prechtl Heinz
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- Abstract:
- An apparently normal early development was one of the initial criteria for classical Rett syndrome. However, several investigators considered Rett syndrome to be a developmental disorder manifesting very soon after birth. Videos of 14 infants with Rett disorder were carefully assessed for their spontaneous movements, in particular general movements (GMs), during the first 4 months of life. A detailed analysis clearly demonstrated that none of the infants had normal GMs. However, a specific abnormal GM pattern could not be detected for Rett disorder. The abnormal GMs described here, and their individual developmental trajectories are different from the abnormal GMs described in infants with acquired brain lesion. Our study is the first to apply specific standardised measures of early spontaneous movements to infants with Rett syndrome, proving conclusively that the disorder is manifest within the first weeks of life.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Age Factors -
- Child -
- Developmental Disabilities - physiopathology
- Dyskinesias - etiology
- Female - etiology
- Humans - etiology
- Infant - etiology
- Methyl-CpG-Binding Protein 2 - genetics
- Mutation - genetics
- Retrospective Studies - genetics
- Rett Syndrome - diagnosis
- Video Recording - methods
- Find related publications in this database (Keywords)
- fidgety movements
- generalised movements
- infant
- spontaneous movements
- video analysis