Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Zobel, G; Ring, E; Kuttnig, M; Grubbauer, HM.
Five years experience with continuous extracorporeal renal support in paediatric intensive care.
Intensive Care Med. 1991; 17(6):315-319
Doi: 10.1007/BF01716188
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- Führende Autor*innen der Med Uni Graz
- Zobel Gerfried
- Co-Autor*innen der Med Uni Graz
- Grubbauer Hans
- Ring Ekkehard
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- Abstract:
- Continuous arterio-venous haemofiltration (CAVH) and continuous veno-venous haemofiltration (CVVH) were used as renal support in 52 critically ill infants and children with acute renal failure. The majority of the patients were on mechanical ventilation (90%) and needed vasopressor support (85%). Uraemia was satisfactorily controlled with both treatment modes. Post-treatment serum urea levels were not different between survivors (94 +/- 8.8 mg/dl) and non-survivors (99.5 +/- 8.8 mg/dl). There were significant differences between survivors and non-survivors in the mean arterial pressure (64.7 +/- 3.8 vs 48.0 +/- 2.2 mmHg, p less than 0.001), the number of organ system failures (2.9 +/- 0.16 vs 3.8 +/- 0.21, p less than 0.025), and the severity of illness assessed by the acute physiologic score for children (APSC 19.4 +/- 1.9 vs 26.3 +/- 1.9, p less than 0.01). The overall mortality was 48%. The mortality in the CVVH group (65%) was higher than in the CAVH group (40%). Death was significantly related to sepsis (p less than 0.005) and multiple system organ failure (p less than 0.005). A major complication during CAVH was one femoral artery thrombosis after 12 days of treatment. Technical problems were only observed during CVVH. CAVH and CVVH are safe and effective methods of continuous renal support for critically ill paediatric patients with multiple system organ failure. CAVH is simpler, needs no specially trained staff and seems to the ideal renal replacement system for critically ill infants.
- Find related publications in this database (using NLM MeSH Indexing)
- Austria - epidemiology
- Blood Flow Velocity - epidemiology
- Body Weight - epidemiology
- Cause of Death - epidemiology
- Child, Preschool - epidemiology
- Female - epidemiology
- Hemofiltration - instrumentation
- Hospitals, Pediatric - instrumentation
- Hospitals, University - instrumentation
- Humans - instrumentation
- Intensive Care Units, Pediatric - instrumentation
- Kidney Failure, Acute - etiology
- Male - etiology
- Severity of Illness Index - etiology
- Survival Rate - etiology
- Find related publications in this database (Keywords)
- Continuous Hemofiltration
- Multiple System Organ Failure
- Pediatric Intensive Care