Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Cull, A; Howat, S; Greimel, E; Waldenstrom, AC; Arraras, J; Kudelka, A; Chauvenet, L; Gould, A; EORTC Quality of Life Group [European Organization for Research and Treatment of Cancer]; Scottish Gynaecological Cancer Trials Group.
Development of a European Organization for Research and Treatment of Cancer questionnaire module to assess the quality of life of ovarian cancer patients in clinical trials: a progress report.
Eur J Cancer. 2001; 37(1):47-53
Doi: 10.1016%2FS0959-8049%2800%2900369-5
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- Co-Autor*innen der Med Uni Graz
- Greimel Elfriede Renate
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- Abstract:
- A questionnaire was developed, according to the European Organization for Research and Treatment of Cancer (EORTC) published guidelines, to supplement the EORTC quality of life questionnaire-core 30 (QLQ-C30) to assess the quality of life (QL) of women with ovarian cancer treated in clinical trials. The provisional 28-item module, OV28, assesses abdominal symptoms; peripheral neuropathy; other chemotherapy side-effects; hormonal symptoms; body image; attitude to disease and treatment; and sexual functioning. The first 24 items of the module (excluding sexual functioning) were included in a UK multicentre trial (SCOTROC). The trial data were used for preliminary scaling analysis. Two problematic items were identified. When these were treated as single items along with the 'other chemotherapy side-effects' the instrument showed excellent scale properties. Mean scale scores discriminated between trial patients pre- and on chemotherapy. This is a promising tool for assessing the QL of women with ovarian cancer. The EORTC international field study (Protocol 15982) to assess more fully the psychometric properties of the OV28 is well underway.
- Find related publications in this database (using NLM MeSH Indexing)
- Antineoplastic Agents - adverse effects
- Clinical Trials - adverse effects
- Female - adverse effects
- Humans - adverse effects
- Middle Aged - adverse effects
- Ovarian Neoplasms - drug therapy
- Quality of Life - drug therapy
- Questionnaires - standards
- Find related publications in this database (Keywords)
- quality of life assessment
- ovarian cancer
- EORTC
- questionnaire