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Selected Publication:
Kocher, AA; Schlechta, B; Kopp, CW; Ehrlich, M; Ankersmit, J; Ofner, P; Langer, F; Berlakovich, GA; Grimm, M; Wolner, E; Laufer, G.
Combined heart and kidney transplantation using a single donor: a single center's experience with nine cases.
Transplantation. 1998; 66(12):1760-1763
Doi: 10.1097/00007890-199812270-00033
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- Co-authors Med Uni Graz
- Ofner-Kopeinig Petra
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- Abstract:
- BACKGROUND: Simultaneous double-organ transplants comprising various organ combinations have become frequent. The purpose of this article is to report on a single center's experience of simultaneous heart and kidney transplantation (HNTX) with particular emphasis on selection criteria and patient outcome. METHODS: From September 1990 to January 1997, nine patients underwent HNTX, receiving both grafts from a single donor selected on ABO blood group compatibility and a negative lymphocytotoxic crossmatch, but without regard to HLA-antigen matching. RESULTS: One patient died of acute humoral rejection of the cardiac graft shortly after surgery. Eight patients are alive and well and have normal cardiac and renal function at a mean follow-up of 44+/-28 months. CONCLUSION: HNTX offers a compelling therapeutic solution in the treatment of advanced cardiac and renal failure in carefully selected patients. Because the heart and kidney rejection episodes were independent of each other, rejection surveillance should be carried out separately for each transplanted organ.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Female -
- Graft Rejection -
- Heart Transplantation - adverse effects
- Histocompatibility Testing - adverse effects
- Humans - adverse effects
- Kidney Transplantation - adverse effects
- Male - adverse effects
- Middle Aged - adverse effects
- Tissue Donors - adverse effects