Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Chaudhry, HR; Hofmann, P; Loimer, N; Kotter, M; Quehenberger, F; Fueger, G.
Prolactin and beta-endorphin serum elevations after ECT in manic patients.
Acta Psychiatr Scand. 2000; 102(5):386-389
Doi: 10.1034%2Fj.1600-0447.2000.102005386.x
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Hofmann Peter
- Co-Autor*innen der Med Uni Graz
- Quehenberger Franz
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- Abstract:
- OBJECTIVE: Alterations in prolactin and beta-endorphin serum levels after ECT are well-established findings in depression. The present study focuses on electroconvulsive therapy (ECT) response patterns of the mentioned parameters in patients suffering from acute mania. METHOD: Following the first three ECTs of a treatment series in 19 patients diagnosed according to DSM-III-R criteria as suffering from mania, blood samples were drawn before, and 20, 30 and 40 minutes after ECT. Serum prolactin and beta-endorphin levels were established in order to gain information about the effects of ECT on different neurotransmitter systems. RESULTS: A significant transient increase in serum prolactin after ECT was found. Furthermore, in females but not males, delta(max)prolactin diminished over the course of treatment as prolactin baseline levels increased. beta-endorphin levels showed a stable transient increase after ECT stimulus regardless from sex or treatment. CONCLUSION: The reported findings reflect those established in depression. This suggests that they are epiphenomenal to ECT.
- Find related publications in this database (using NLM MeSH Indexing)
- Acute Disease -
- Adult -
- Bipolar Disorder - blood
- Depression - blood
- Electroconvulsive Therapy - blood
- Female - blood
- Humans - blood
- Logistic Models - blood
- Male - blood
- Middle Aged - blood
- Prolactin - blood
- beta-Endorphin - blood
- Find related publications in this database (Keywords)
- electroconvulsive therapy
- prolactin
- beta-endorphin
- mania