Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Tunus, G; Pilger, U; Aberer, E.
Severe initial manifestations of psoriasis in staphylococcal infections
Wien Klin Wochenschr. 2001; 113(19):747-751
(- Case Report)
Web of Science
PubMed
- Führende Autor*innen der Med Uni Graz
- Aberer Elisabeth
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- Abstract:
- Psoriasis vulgaris is a chronic disease with certain restrictions of life quality, but rarely life threatening. However, psoriatic erythroderma or pustular psoriasis can be a diagnostic or therapeutic challenge, especially when it arises as the primary manifestation of disease. Here we report on two patients with severe clinical course of pustular psoriasis or psoriatic erythroderma, both possibly induced by Staphylococcus aureus. This microorganism was cultivated from skin scrapings in both patients, in the patient with pustular psoriasis from the blood, and in the patient with erythroderma from the nose. Both patients had anti-staphylolysin antibodies. Both patients showed resolution of their disease only by the action of systemic antibiotics. We suggest that staphylococcal superantigens which activate T-cells might play an important role in severe psoriasis by inducing a systemic Köbner phenomenon and thus a progression of disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Adrenal Cortex Hormones - administration and dosage
- Aged - administration and dosage
- Aged, 80 and over - administration and dosage
- Anti-Bacterial Agents - administration and dosage
- Biopsy - administration and dosage
- Female - administration and dosage
- Humans - administration and dosage
- Middle Aged - administration and dosage
- Parapsoriasis - etiology
- Psoriasis - drug therapy
- Skin - pathology
- Staphylococcal Skin Infections - complications
- Staphylococcus aureus - complications
- Time Factors - complications
- Find related publications in this database (Keywords)
- Staphylococcus aureus
- psoriasis vulgaris
- erythroderma
- pustular psoriasis
- staphylococcal toxins