Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Emberger, W; Behmel, A; Tschernigg, M; Seewann, HL; Petek, E; Kroisel, PM; Wagner, K.
Chronic myeloid leukemia with a rare variant Philadelphia translocation: t(9;10;22)(q34;q22;q11).
Cancer Genet Cytogenet. 2001; 129(1):76-79
Doi: 10.1016/S0165-4608(01)00417-4
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- Führende Autor*innen der Med Uni Graz
- Emberger Werner
- Co-Autor*innen der Med Uni Graz
- Kroisel Peter
- Petek Erwin
- Tschernigg Michaela
- Wagner Klaus
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- Abstract:
- We report a 59-year-old, male, chronic myeloid leukemia patient with a rare variant Philadelphia (Ph) translocation t(9;10;22)(q34;q22;q11). Fluorescence in situ hybridization with whole chromosome paints was used to confirm the cytogenetic findings. With a BCR/ABL-specific probe, the known rearrangement on the derivative chromosome 22 was found. The prognostic implications as well as the relevance of the additional breakpoint region 10q22 are discussed.
- Find related publications in this database (using NLM MeSH Indexing)
- Chromosomes, Human, Pair 10 -
- Chromosomes, Human, Pair 22 -
- Chromosomes, Human, Pair 9 -
- Humans -
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics
- Male -
- Middle Aged -
- Philadelphia Chromosome -
- Translocation, Genetic -