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Selected Publication:
Tamussino, KF; Reich, O; Gücer, F; Moser, F; Zivkovic, F; Lang, PF; Winter, R.
Parametrial spread in patients with endometrial carcinoma undergoing radical hysterectomy.
Int J Gynecol Cancer. 2000; 10(4):313-317
Doi: 10.1046/j.1525-1438.2000.010004313.x
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- Leading authors Med Uni Graz
- Tamussino Karl
- Co-authors Med Uni Graz
- Reich Olaf
- Winter Raimund
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- Abstract:
- The objective of this paper is to study parametrial involvement in patients with endometrial carcinoma undergoing radical hysterectomy. We reviewed indications for surgery, pathology findings, and outcome of a series of 24 patients with endometrial carcinoma who underwent radical hysterectomy. The uterus, cervix and parametrial tissue were processed as step-serial sections. Histologically, 16 patients (67%) had carcinoma involving the cervix. Two of these patients (8%) had frank histologic parametrial involvement and four (17%) had disease extending to the transitional zone of the cervix. Parametrial involvement was continuous and seen only in patients with involvement of the cervical stroma. Six patients (25%) had pelvic node metastases. With a median follow-up of 53 months (range 2-140), four patients (17%) developed recurrences (all within 24 months). Twelve patients (50%), including one of the two with parametrial invasion, were free of disease for 5 years or longer. We conclude that direct parametrial extension can occur in locally advanced endometrial cancer. Radical hysterectomy with lymphadenectomy can be an adequate operation for such patients.
- Find related publications in this database (Keywords)
- endometrial cancer
- radical hysterectomy
- spred
- treatment