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Selected Publication:
Obermair, A; Petru, E; Windbichler, G; Peters-Engl, C; Graf, AH; Stummvoll, W; Kaider, A; Kurschel, S; Kölbl, H; Sevelda, P.
Significance of pretreatment serum hemoglobin and survival in epithelial ovarian cancer.
ONCOL REP 2000 7: 639-644.
Doi: 10.3892/or.7.3.639
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- Co-authors Med Uni Graz
- Kurschel-Lackner Senta
- Petru Edgar
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- Abstract:
- Tumor anemia is common in patients with malignant tumors and it was repeatedly demonstrated to be associated with impaired prognosis in patients with malignant tumors. We conducted a retrospective analysis based on 553 patients with histologically proven epithelial ovarian cancer. Blood hemoglobin levels were determined before surgery and patients with values <12 g/dl were considered anemic. Data analysis included univariate and multiple Cox models. Tumor anemia was present in 143 (25.9%) patients before surgery. Tumor anemia was present in 143 (25.9%) patients before surgery. In a multivariate Cox model, pretreatment hemoglobin values proved to be an independent prognostic factor for patients with stage I-II epithelial ovarian cancer (n=203), but failed to attain significance in patients with stage III-IV disease (n=350). Tumor anemia defined as pretreatment hemoglobin values <12 g/dl may indicate patients with stage I and II epithelial ovarian cancer, who are at increased risk of relapse.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenocarcinoma, Mucinous - blood
- Adult - blood
- Aged - blood
- Anemia - blood
- Carcinoma - blood
- Carcinoma, Endometrioid - blood
- Female - blood
- Follow-Up Studies - blood
- Hemoglobins - analysis
- Humans - analysis
- Middle Aged - analysis
- Multivariate Analysis - analysis
- Neoplasm Staging - analysis
- Ovarian Neoplasms - blood
- Predictive Value of Tests - blood
- Proportional Hazards Models - blood
- Research Support, Non-U.S. Gov't - blood
- Retrospective Studies - blood
- Time Factors - blood
- Find related publications in this database (Keywords)
- anemia
- hemoglobin
- ovarian cancer
- prognosis