Medizinische Universität Graz - Research portal
Selected Publication:
Schmidt, R; Willeit, J; Brainin, M.
Stroke: Protective factors
NEUROPSYCHIATRIE 2000 14: 3-11.
Web of Science
- Leading authors Med Uni Graz
- Schmidt Reinhold
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- Abstract:
- We reviewed the current literature on protective factors for stroke. Physical activity and salt restriction have a proven effect with data for salt restriction existing for stroke mortality only. There is evidence from observational but not interventional studies for protective effects of fruit- and vegetable-rich nutrition, optimal vitamin B-6, B-12 and folic acid plasma levels as well as mild-to-moderate alcohol consumption. Cholesterol-lowering diet and drugs other than statins yielded no reduction in stroke risk. Statins reduce strokes in patients with myocardial infarction, yet interventional trials with stroke as the primary outcome measure are still pending. Similar evidence exists in terms of postmenopausal hormone replacement and blood donation in order to reduce the body's iron pool. Vitamin E and beta-caroten supplements failed to decrease the incidence of strokes in large trials. Similar findings have been reported for the general use of acetylsalicylic acid. However, metaanalyses indicate that acetylsalicylic acid may be beneficial in high-risk groups.
- Find related publications in this database (Keywords)
- stroke
- primary prevention
- protection