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Weber, C; Weninger, M; Klebermass, K; Reiter, G; Wiesinger-Eidenberger, G; Brandauer, M; Kraschl, R; Lingitz, K; Grassl-Jurek, R; Sterniste, W; Balluch, B; Kolmer, M; Bruckner, R; Schweintzger, G; Salzer, H; Rath, I; Kubitsch, P; Zissler, W; Müller, W; Urlesberger, B.
Mortality and morbidity in extremely preterm infants (22 to 26 weeks of gestation): Austria 1999-2001.
Wien Klin Wochenschr. 2005; 117(21-22):740-746
Doi: 10.1007/s00508-005-0468-y
Web of Science
PubMed
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- Leading authors Med Uni Graz
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Urlesberger Berndt
- Co-authors Med Uni Graz
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Müller Wilhelm
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- Abstract:
- OBJECTIVE: The aim of this retrospective study was to analyze the mortality and morbidity for extremely preterm infants with a gestational age from 22 to 26 weeks. All infants were born in Austria during the years 1999-2001. METHODS: Data were collected from 16 neonatal intensive care units in Austria. Main outcome criteria were mortality, the rates of chronic lung disease (CLD) and severe retinopathy of prematurity (ROP, stage > or =3) to determine the short-term outcome; the rate of cerebral palsy (CP) at the corrected age of twelve months to assess the long-term outcome. RESULTS: Overall, 796 preterm infants with a gestational age less than 27 weeks were born in Austria and 581 (73%) were registered as live-born infants. Of those live born, 508 (87%) were analyzed. The mortality rates were 83%, 76%, 43%, 26% and 13% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. The rates of CLD were 33% (22 weeks), 36% (23 weeks), 42% (24 weeks), 31% (25 weeks) and 22% (26 weeks). The rates of ROP of stage > or =3 were 0% (22 weeks), 29% (23 weeks), 23% (24 weeks), 18% (25 weeks) and 10% (26 weeks). The rates of CP at the corrected age of 12 months were 33%, 50%, 33%, 26% and 25% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. CONCLUSIONS: The results of this national study are in accordance with the international literature: mortality and morbidity increased with decreasing gestational age.
- Find related publications in this database (using NLM MeSH Indexing)
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Age Distribution -
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Birth Weight -
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Cerebral Palsy - mortality
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Cohort Studies - mortality
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Comorbidity - mortality
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Female - mortality
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Gestational Age - mortality
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Humans - mortality
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Infant, Newborn - mortality
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Infant, Premature, Diseases - epidemiology
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Male - epidemiology
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Premature Birth - mortality
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Prevalence - mortality
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Registries - mortality
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Retrospective Studies - mortality
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Risk Assessment - methods
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Risk Factors - methods
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Sex Distribution - methods
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Survival Analysis - methods
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Survival Rate - methods
- Find related publications in this database (Keywords)
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extremely preterm infant
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mortality
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morbidity
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outcome
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Austria