Medizinische Universität Graz - Research portal
Selected Publication:
Unger, F; Walch, C; Haselsberger, K; Papaefthymiou, G; Trummer, M; Eustacchio, S; Pendl, G.
Radiosurgery of vestibular schwannomas: a minimally invasive alternative to microsurgery.
Acta Neurochir (Wien). 1999; 141(12):1281-1285
Doi: 10.1007%2Fs007010050431
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- Leading authors Med Uni Graz
- Unger Frank
- Co-authors Med Uni Graz
- Eustacchio Sandro
- Haselsberger Klaus
- Papaefthymiou Georgios
- Trummer Martin
- Walch Christian
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- Abstract:
- From April 1992 till December 1998 stereotactic radiosurgery (Gamma Knife) was applied to 192 patients with vestibular schwannomas. 56 of them had radiosurgery as primary treatment modality and were followed-up for at least 4 years (48-80 months, median 62). Without fatal complications, control of tumour growth was achieved in all but three cases, useful hearing being preserved in more than one half of the patients (62%). The neurological state improved in 30 patients (54%). Irradiation-associated adverse effects (18%) comprised neurological signs (incomplete facial palsy, four cases (two recovered completely), and mild trigeminal neuropathy, three cases, respectively) and morphological changes (three patients) marked by an enlargement of pre-existing cystic components calling for additional surgical treatment: Microsurgical decompression was performed in two cases, the third patient underwent a shunting procedure because of hydrocephalus formation. Based on the present data, radiosurgery represents an effective treatment for vestibular schwannomas associated with an exceptionally low mortality rate and a good quality of life. With respect to the preservation of cranial nerve function, results are comparable to microsurgical resection. A short duration of hospitalization and a quick return to normal activities constitute further advantages and contribute to cost effectiveness in public health care.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Female -
- Follow-Up Studies -
- Humans -
- Magnetic Resonance Imaging -
- Male -
- Microsurgery -
- Middle Aged -
- Neurologic Examination -
- Neuroma, Acoustic - diagnosis
- Postoperative Complications - diagnosis
- Radiosurgery - diagnosis
- Reoperation - diagnosis
- Surgical Procedures, Minimally Invasive - diagnosis
- Tomography, X-Ray Computed - diagnosis
- Find related publications in this database (Keywords)
- acoustic neuroma
- cranial nerve preservation
- Gamma Knife
- stereotactic radiosurgery
- vestibular schwannoma