Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Leys, D; Englund, E; Del Ser, T; Inzitari, D; Fazekas, F; Bornstein, N; Erkinjuntti, T; Bowler, JV; Pantoni, L; Parnetti, L; De Reuck, J; Ferro, J; Bogousslavsky, J.
White matter changes in stroke patients. Relationship with stroke subtype and outcome.
Eur Neurol. 1999; 42(2):67-75
Doi: 10.1159/000069414
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Fazekas Franz
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- Abstract:
- White matter changes (WMC), detected by imaging techniques, are frequent in stroke patients. The aim of the study was to determine how WMC relate to stroke subtypes and to stroke outcome. We made a systematic Medline search for articles appearing with two of the following key words: either 'WMC or white matter lesions or leukoencephalopathy or leukoaraiosis' and 'stroke or cerebral infarct or cerebral hemorrhage or cerebrovascular disease or transient ischemic attack (TIA)'. WMC, as defined radiologically, are present in up to 44% of patients with stroke or TIA and in 50% of patients with vascular dementia. WMC are more frequent in patients with lacunar infarcts, deep intracerebral hemorrhages, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy and cerebral amyloid angiopathy. After an acute ischemic stroke, WMC are associated with a higher risk of death or dependency, recurrent stroke of any type, cerebral bleeding under anticoagulation, myocardial infarction, and poststroke dementia. WMC in stroke patients are often associated with small-vessel disease and lead to a higher risk of death, and poor cardiac and neurological outcome. However, several questions remain open and need further investigations.
- Find related publications in this database (using NLM MeSH Indexing)
- Age Factors -
- Brain - pathology
- Brain Diseases - etiology
- Cerebrovascular Accident - complications
- Humans - complications
- Find related publications in this database (Keywords)
- Stroke
- Cerebral Infarct
- Cerebral Hemorrhage
- Transient Ischemic Attack
- Stroke Subtype
- Stroke Outcome
- White Matter
- Leukoaraiosis
- Leukoencephalopathy
- Vascular Dementia