Medizinische Universität Graz - Research portal
Selected Publication:
Kenner, L; Schwarzl, F; Moshammer, H; Haas, F; Hoefler, G; Pierer, G.
Venous thrombosis in a replanted finger with underlying factor V Leiden mutation.
Br J Plast Surg. 1998; 51(1):57-58
Doi: 10.1016/S0007-1226(97)90176-4
(- Case Report)
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- Leading authors Med Uni Graz
- Kenner Lukas
- Co-authors Med Uni Graz
- Haas Franz
- Höfler Gerald
- Schwarzl Franz
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- Abstract:
- Resistance to activated protein C (APC resistance) was described recently as a cause for thrombophilia. APC inactivates coagulation co-factors Va and VIIIa. A single base-pair mutation changing Arg506 to Gln at the APC cleavage site of the factor V gene leads to a factor V Leiden variant, which is the most frequent cause of APC resistance. Recently, its role in peripheral venous thrombosis during pregnancy was described. We here report a case with thrombosis of the venous anastomoses after finger replantation with resistance to activated protein C associated with factor V Leiden mutation.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Factor V - genetics
- Finger Injuries - surgery
- Humans -
- Male -
- Mutation -
- Postoperative Complications -
- Protein C - physiology
- Replantation -
- Thrombophlebitis - genetics