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Selected Publication:
Hofmann-Wellenhof, R; Soyer, HP; Wolf, IH; Smolle, J; Reischle, S; Rieger, E; Kenet, RO; Wolf, P; Kerl, H.
Ultraviolet radiation of melanocytic nevi: a dermoscopic study.
Arch Dermatol. 1998; 134(7):845-850
Doi: 10.1001/archderm.134.7.845
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- Leading authors Med Uni Graz
- Hofmann-Wellenhof Rainer
- Soyer Hans Peter
- Co-authors Med Uni Graz
- Kerl Helmut
- Smolle Josef
- Wolf Ingrid
- Wolf Peter
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- Abstract:
- UV radiation can lead to clinical, histological, and ultrastructural changes in melanocytic nevi. In this study, we investigated whether exposure to 2 minimal erythema doses of UV radiation induces changes in the dermoscopic image of acquired melanocytic nevi. Fifteen melanocytic nevi were exposed to 2 minimal erythema doses of UV radiation. Differences in dermoscopic parameters (asymmetry, border, erythema, and telangiectasias in the nevus; pigmentation; hypopigmented areas; presence, regularity, and sharpness of pigment network; and brown-black globules) in digital dermoscopic images taken before and 3, 7, 14, and 28 days after UV irradiation were scored. Three days after UV irradiation, the borders of nevi were more faded (P<.02), the nevi were darker brown (P<.02), the hypopigmented areas were smaller (P<.02), and the pigment network structures were more faded (P<.007) and less prominent (P<.02) than before UV irradiation. Seven days after UV irradiation, pigmented globules have also grown (P<.05). After 28 days, all parameters, except hypopigmented areas, were essentially the same as before UV irradiation. UV irradiation of melanocytic nevi with 2 minimal erythema doses induces transient changes in their dermoscopic appearance that are sometimes suggestive of malignant melanoma.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Dose-Response Relationship, Radiation -
- Erythema - etiology Erythema - pathology Erythema - physiopathology
- Humans -
- Male -
- Microscopy - methods
- Nevus, Pigmented - pathology Nevus, Pigmented - physiopathology
- Radiation Dosage -
- Radiation Protection -
- Skin - pathology Skin - physiopathology Skin - radiation effects
- Skin Pigmentation - physiology Skin Pigmentation - radiation effects
- Time Factors -
- Ultraviolet Rays - adverse effects