Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Hofmann, P; Gangadhar, BN; Probst, C; Koinig, G; Hatzinger, R.
TSH response to TRH and ECT.
J AFFECT DISORDERS. 1994; 32(2): 127-131.
Doi: 10.1016%2F0165-0327%2894%2990070-1
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- Führende Autor*innen der Med Uni Graz
- Hofmann Peter
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- Abstract:
- In 31 female patients diagnosed according to DSM-III-R criteria as suffering from 'functional' psychosis (e.g., major depression, schizophrenia, mania) TRH tests were administered before, during and after a course of electroconvulsive therapy (ECT) to investigate the effects of ECT on HPT (hypothalamic-pituitary-thyroid) axis as well as the predictive value of TSH response to TRH on treatment outcome. In 20 patients all three TRH tests were available; no significant changes in the mean TSH response were found over the course of ECT; however, a change towards blunted TSH response at the end of treatment was observed. The initial TSH response did not predict the treatment outcome.
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