Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schwinger, W; Urban, C; Lackner, H.
Clinical experiences with adrenaline as therapy and prevention of E. coli-L-asparaginase-induced anaphylaxis
KLIN PADIAT. 1992; 204(4): 274-276.
Doi: 10.1055/s-2007-1025359
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Schwinger Wolfgang
- Co-Autor*innen der Med Uni Graz
- Lackner Herwig
- Urban Ernst-Christian
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Management of E.-coli L-asparaginase induced anaphylaxis mainly consists of application of i.v. epinephrine but also in the withdrawal of this drug. Despite of this firm recommendation we have shown in 7 patients with E. coli L-asparaginase induced anaphylaxis, that further application of the drug is possible in the presence of a continuous epinephrine infusion (0.01-0.02 mg/kg) started one hour before and finished one hour after the concomittant infusion of the E.-coli L-asparaginase. In none of the patients there was a second event of anaphylaxis even though most of the patients still had to continue on E.-coli L-asparaginase with an average of more than 6 infusion.
- Find related publications in this database (using NLM MeSH Indexing)
- Anaphylaxis - chemically induced
- Antineoplastic Combined Chemotherapy Protocols - adverse effects
- Asparaginase - administration and dosage
- Child - administration and dosage
- Drug Administration Schedule - administration and dosage
- Epinephrine - administration and dosage
- Female - administration and dosage
- Humans - administration and dosage
- Injections, Intravenous - administration and dosage
- Leukemia, Lymphocytic, Acute - drug therapy
- Lymphoma, Non-Hodgkin - drug therapy
- Male - drug therapy