Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Gücer, F; Moser, F; Tamussino, K; Reich, O; Haas, J; Arikan, G; Petru, E; Winter, R.
Thrombocytosis as a prognostic factor in endometrial carcinoma.
Gynecol Oncol. 1998; 70(2):210-214
Doi: 10.1006/gyno.1998.5078
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- Co-Autor*innen der Med Uni Graz
- Haas Josef
- Petru Edgar
- Reich Olaf
- Tamussino Karl
- Winter Raimund
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- Abstract:
- We reviewed the prevalence of thrombocytosis (platelet count >/=400, 000/microL) and its association with outcome in 135 consecutive endometrial carcinoma patients and compared the platelet count with other prognostic factors. Nineteen of 135 patients (14%) had thrombocytosis. Thrombocytosis was significantly more frequent in advanced disease (stage II-IV), unfavorable grade (G2 and G3), deep myometrial invasion, and lymph-vascular space invasion. The overall 5-year survival rate was 92%. The 5-year survival rate of the 19 patients with thrombocytosis was significantly worse than that of the patients without thrombocytosis (61 vs 96%, P < 0.0001). The recurrence rate was significantly higher in patients with thrombocytosis than in those with a platelet count <400,000/microL (7 vs 32%, P < 0.005). In a multivariate analysis, thrombocytosis continued to be a predictor of worse prognosis. In conclusion, we found thrombocytosis to be a prognostic factor for survival in patients with endometrial carcinoma.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Endometrial Neoplasms - complications
- Female - complications
- Humans - complications
- Middle Aged - complications
- Multivariate Analysis - complications
- Neoplasm Staging - complications
- Platelet Count - complications
- Prognosis - complications
- Survival Rate - complications
- Thrombocytosis - complications
- Find related publications in this database (Keywords)
- Endometrial Carcinoma
- Thrombocytosis
- Platelet Count
- Prognosis