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Schmid, F; Sommer, G; Rappolt, M; Schulze-Bauer, CA; Regitnig, P; Holzapfel, GA; Laggner, P; Amenitsch, H.
In situ tensile testing of human aortas by time-resolved small-angle X-ray scattering.
J SYNCHROTRON RADIAT. 2005; 12: 727-733.
Doi: 10.1107/S0909049505012549
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- Co-Autor*innen der Med Uni Graz
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Regitnig Peter
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- Abstract:
- The collagen diffraction patterns of human aortas under uniaxial tensile test conditions have been investigated by synchrotron small-angle X-ray scattering. Using a recently designed tensile testing device the orientation and d-spacing of the collagen fibers in the adventitial layer have been measured in situ with the macroscopic force and sample stretching under physiological conditions. The results show a direct relation between the orientation and extension of the collagen fibers on the nanoscopic level and the macroscopic stress and strain. This is attributed first to a straightening, second to a reorientation of the collagen fibers, and third to an uptake of the increasing loads by the collagen fibers.
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Aorta - chemistry
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Biomechanics - chemistry
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Collagen - chemistry
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Elasticity - chemistry
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Humans - chemistry
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Scattering, Radiation - chemistry
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Synchrotrons - chemistry
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Tensile Strength - chemistry
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X-Ray Diffraction - instrumentation
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human tissue
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biomechanics
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artery
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small-angle X-ray scattering
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collagen
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fiber diffraction
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tensile testing